Each duly filed application for a plant variety certificate shall be published in the Plant Variety Protection Bulletin referred to in Article 59 below. The particular purpose of such publication shall be to inform all persons having an interest therein of the application for a plant variety certificate. As from the day of publication referred to in the preceding paragraphs, all persons may inspect the application as entered in the National Register of Applications for Plant Variety Certificates. Article 46 Within a period of three months as from the date of publication referred to in the preceding Article, any person having an interest therein may submit observations in writing to the Competent Office. Such observations shall be reasoned and may only concern the fact that the variety applied for is not eligible for protection in accordance with the provisions of Articles 5 and 14 of this Law. Article 47 Any opposition concerning the breeder’s claim to the variety for which a plant variety certificate is sought shall be submitted directly to the competent courts. It shall be entered in the National Register of Applications for Plant Variety Certificates. Article 48 Where the variety denomination proposed by the breeder or his successor in title was not included in the initial application or where the breeder proposes, at the request of the Office, a new denomination, such denomination shall be published in the Bulletin referred to in Article 59 below. Article 49 Any observations submitted shall be notified by the Competent Office to the holder of the application. The holder shall have a period of one month as from the day on which he confirms receipt of the notification to submit his arguments or his defense. Article 50 Once the application has been duly registered, the Competent Office shall prosecute the application for a plant variety certificate and, where appropriate, examine the observations relating thereto.